Journal of Clinical and Aesthetic Dermatology

MAY 2018

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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Page 12 of 55

© 2018 Aclaris Therapeutics, Inc. All rights reserved. PP-ESK-US-0235 04/18. ESKATA is a trademark of Aclaris Therapeutics, Inc. Bring the benefit of ESKATA to your practice. Visit now TOPICAL For external, topical use only IN-OFFICE APPLICATION By a healthcare provider SELF-PAY Self-pay billing model Indications and Usage ESKATA™ (hydrogen peroxide) topical solution, 40% (w/w) is indicated for the treatment of seborrheic keratoses that are raised. IMPORTANT SAFETY INFORMATION WARNINGS AND PRECAUTIONS Do not apply ESKATA to the eyes or mucous membranes. Avoid treating seborrheic keratoses within the orbital rim. Direct contact with the eye can cause corneal injury (erosion, ulceration, perforation, and scarring), chemical conjunctivitis, eyelid edema, severe eye pain or permanent eye injury, including blindness. If accidental exposure occurs, flush with water for 15 to 30 minutes, initiate monitoring and further evaluation as appropriate. Skin reactions occurred in the treatment area a er application of ESKATA. Severe local skin reactions included erosion, ulceration, vesiculation and scarring. Do not retreat until the skin has recovered from any reaction caused by the previous treatment. MOST COMMON ADVERSE REACTIONS The most common adverse reactions include erythema (99%), stinging (97%), edema (91%), scaling (90%), crusting (81%), and pruritus (58%). CONTRAINDICATIONS None. DOSAGE AND ADMINISTRATION ESKATA is to be administered by a healthcare provider. For topical use only. Not for oral, ophthalmic, or intravaginal use. Not for open or infected seborrheic keratoses. Please see brief summary of full Prescribing Information for ESKATA (hydrogen peroxide) topical solution, 40% (w/w). NOW AVAILABLE TO ORDER For the treatment of raised seborrheic keratoses

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