Journal of Clinical and Aesthetic Dermatology

DEC 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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39 JCAD JOURNAL OF CLINICAL AND AESTHETIC DERMATOLOGY December 2017 • Volume 10 • Number 12 O R I G I N A L R E S E A R C H calculations were done using computer program SPSS version 15 for Microsoft Windows (IBM Corp., Armonk, New York, United States) RESULTS The cause of burn scars included thermal burns from heated fluids in 11 patients (55%) and fire in nine patients (45%). Treated burn scars were located on the arms in 14 patients (70%), the thighs in two patients (10%), the chest in two patients (10%), the breast in one patient (5%), and the abdomen in one patient (5%). Scar duration ranged from 1 to 30 years (mean: 12.30±8.70 years). Previous treatment modalities included intralesional steroids, grafting, surgical release, and topical treatment (Table 3). Seventeen patients completed the entire treatment and follow-up protocol. One patient dropped out after the second treatment session due to personal issues and two patients were not able attend the final follow-up session (which ocurred two months after the last session) (Figure 2). Clinical results. Primary outcome scores showed significant reduction (p<0.001) (Figure 3, Table 4). The percentage improvement of each score is listed in Table 5. The percentage improvement in each variable of VSS is listed in Table 6, with pliability being the most significantly improved item (p<0.0001). The percentage improvement in each variable of the POSAS is listed in Table 7, with relief being the most significantly improved item (p=0.0071). Scar duration negatively influenced the percentage improvement in VSS, but not the percentage improvement in total POSAS (r= -0.608, p=0.010 and r= -0.465, p=0.06, respectively). However, neither the age of the patient nor site of the scar affected the percentage improvement of both scores. Prolonged erythema was experienced by four patients (23.5%). Seven patients experienced pain following the laser session, with four patients (23.5%) experiencing mild pain and three patients (17.6%) experiencing moderate pain. The pain was generally tolerable, lasting 1 to 6 days (mean: 2.71±1.70 days). Transient swelling following sessions was experienced by three patients (17.6%) lasting from 1 to 3 days (mean: 2±1 days). Hyperpigmentation developed in three patients (17.6%) and FIGURE 2. A flow chart demonstrating the subjects recruited in the study FIGURE 3. Demonstration of clinical response, before treatment (A) and after treatment (B)—The patient showed a 31% improvement in VSS and a 40 percent improvement in total POSAS, with relief being the most improved parameter. A B

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