Journal of Clinical and Aesthetic Dermatology

JUN 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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53 JCAD journal of clinical and aesthetic dermatology June 2017 • volume 10 • Number 6 r E v I E w fractional lasers and acne scars, fractional lasers and melasma, fractional lasers and skin rejuvenation, fractional lasers and photodamage, fractional lasers and striae, fractional lasers and traumatic/surgical scars. the term fractional lasers was also combined with skin type search: fractional lasers and dark skin, fractional laser and ethnic skin, fractional laser and Fitzpatrick skin photo types, fractional lasers and skin of color and fractional lasers with asian skin. a free text search of keywords, including fractional resurfacing, nonablative lasers, Fitzpatrick skin type, skin of color, ethnic skin, asian skin, african americans, afro-Caribbean, and Hispanics was also executed. appropriate filters were used to limit the search to only english language and studies involving human subjects. all the titles and abstracts were screened for relevance to our topic. thereafter, full texts of all the relevant articles were reviewed to fit their inclusion/exclusion criteria (table 2). the inclusion criteria required articles to assess the use of nonablative fractional lasers for any dermatological indication in skin of color subjects. Where applicable, studies comparing nonablative fractional lasers with other treatment modalities were also included. articles limiting themselves to traditional lasers and ablative fractional lasers were excluded. the authors also excluded studies that were limited to sPts i to iii or failed to mention the sPt of their target population. review articles, commentaries, letters, and posters were also excluded. references of all the included articles were reviewed to ensure completeness. an overview of the literature search is outlined in Figure 1. DATA EXTRAC TION AND ANALYSIS Forty-eight articles that met the authors' inclusion/exclusion criteria were identified. these were classified according to their study design, dermatologic indication and sPts included (Figures 2, 3 and 4). randomized controlled trials (rCts) and prospective right/left comparison studies (PrlCs) were further determined to be either high quality or low quality depending on whether they were placebo controlled and double blinded. open-label trials (olts) were classified based on the number of patients involved in the study. thereafter, each study was assigned levels of evidence according to the Modified Criteria published by oxford Center of evidence based Figure 1. Overview of literature search

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