Journal of Clinical and Aesthetic Dermatology

JUN 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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44 JCAD journal of clinical and aesthetic dermatology June 2017 • Volume 10 • number 6 I Mature skin is prone to bruising, resulting in a condition known as actinic purpura, characterized by unsightly ecchymosis and purple patches. Similar to other skin conditions, the incidence of actinic purpura increases with advancing age and occurs with equal frequency among men and women. The unsightly appearance of actinic purpura may be a source of emotional distress among the elderly. A new product has been formulated specifically for the treatment of actinic purpura. This product contains retinol, α- hydroxy acids, arnica oil, ceramides, niacinamide, and phytonadione, which effectively treat actinic purpura by improving local circulation, thickening the skin, and repairing the skin barrier. The objective of this paper is to review the beneficial properties of these ingredients and their respective roles in the treatment of actinic purpura. J Clin Aesthet Dermatol. 2017;10(6):44–50. A b S T R A C T R E v I E W Treatment of Actinic Purpura ROGER I. CEILLEY, MD Dermatology PC, West Des Moines, Iowa In recent years, the incidence of actinic purpura has increased substantially among the older patients in my dermatology practice. although not a serious condition, its unsightly appearance is a significant cause of anxiety and the principle available treatment has been reassurance that the lesions will eventually resolve. the goal of this paper is to briefly review actinic purpura and describe a new product specifically developed for the treatment of actinic purpura and the prevention of future lesions. AGING SKIN AND THE AGING POPULATION skin aging is a complex process associated with cumulative Dna damage 1 due to intrinsic factors, such as the action of reactive oxygen species, 2 and exogenous factors including exposure to ultraviolet light. 3 the skin becomes thinner and less elastic (solar elastosis), 4 and the barrier function of the skin decreases due to depletion of lipids in the stratum corneum. 5 this fragility syndrome has been termed dermatoporosis. 6 changes in normal skin physiology include increased susceptibility to infection, diminished superficial pain Disclosure: The author acknowledges the editorial assistance of Dr. Carl S. Hornfeldt, Apothekon, Inc., with funding provided by Ferndale Healthcare. Author correspondence: Roger I. Ceilley, MD; E-mail:

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