Journal of Clinical and Aesthetic Dermatology

AUG 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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54 JCAD JOURNAL OF CLINICAL AND AESTHETIC DERMATOLOGY august 2017 • volume 10 • number 8 r e v i e w surface pH, sebum content, and stratum corneum hydration with age and gender in a large chinese population. Skin Pharmacol Physiol. 2009;22:190–199. 10. wan mJ, su Xy, Zheng y, et al. seasonal variability in the biophysical properties of forehead skin in women in guangzhou city, china. Int J Dermatol. 2015;54:1319–1324. 11. roh m, Han m, kim d, chung k. sebum output as a factor contributing to the size of facial pores. Br J Dermatol. 2006;155:890–894. 12. sugiyama-nakagiri y, sugatak, Hachiya a, et al. ethnic diserences in the structural properties of facial skin. J Dermatol Sci. 2009;53:135–139. 13. Fritsch m, Orfanos cd, Zouboulis cc. sebocytes are the key regulators of androgen homeostasis in human skin. J Invest Dermatol. 2001;116:793–800. 14. Zouboulis cc, Frimmel s, Ortmann J, et al. sebaceous glands. in: Hoath sB, maibach Hi, eds. Neonatal Skin: Structure and Function. 2nd ed. Basel: taylor and Francis; 2003:59–88. 15. Fluhr Jw, mao-Qiang m, Brown Be, et al. glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice. J Invest Dermatol. 2003;120:728–737. 16. lee d-y, yamasaki k, Zouboulis cc, et al. sebocytes express functional cathelicidin antimicrobial peptides and can act to kill Propionibacterium acnes. J Invest Dermatol. 2008;128:1863–1866. 17. Brand n, Petkovich m, krust a, et al. identification of a second human retinoic acid receptor. Nature. 1988;332:850–853. 18. Fisher gJ, talwar Hs, Xiao JH, et al. immunological identification and functional quantification of retinoic acid and retinoid X receptor proteins in human skin. J Biol Chem. 1994;269:20629–20635. 19. duell ea, astrom a, gritths ce, et al. Human skin levels of retinoic acid and cytochrome P-450- derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate rar-mediated transcription in vitro. 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