Journal of Clinical and Aesthetic Dermatology

JUN 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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Temporary facial blushing and/or flushing were reported by approximately half of the participants in both cohorts. The most bothersome clinical manifestations at the time of the survey were blushing and/or flushing in the ETR cohort, which was significantly greater than that reported by participants in the PPR cohort (p=0.0001; Figure 2B). In the PPR cohort, the most common bothersome clinical manifestations were facial bumps and/or pimples, reported by a significantly greater proportion of participants versus the ETR cohort (p<0.0001). Burning and/or stinging skin, skin thickening, and skin swelling were also more common in the PPR cohort. Findings for the SA-RFR and for the Symptom Assessment for Rosacea Facial Bumps and Pimples questionnaire are shown in Supplementary Figure S1. Almost all participants in both cohorts characterized facial redness as "somewhat red" or "a little red"; similarly, almost all participants in both cohorts described the amount of their face that was red because of rosacea as "some of my face" or "a little of my face." While 48.7 percent of participants in the ETR cohort reported that their face felt at least a little warm because of facial redness, a greater, although not significantly greater, proportion of participants in the PPR cohort (60.7%; p=0.0107) reported that their faces were a little to very warm because of rosacea facial redness. Significantly more patients in the PPR cohort indicated that at least "a little of 22 JCAD journal of clinical and aesthetic dermatology June 2017 • Volume 10 • Number 6 T a b l e 2 . C l i n i c a l c h a r a c t e r i s t i c s P A R A M E T E R E T R C N = 4 0 9 ) P P R C N = 1 9 1 ) Body mass index n 377 179 M ean (SD) 2 9.6 (7.04) 3 0.3 (7.55) Median (range) 28.3 (15.5, 59.6) 28.9 (17.2, 64.0) F itzpatrick skin phototype, n (%) I 62 (15.2) 25 (13.1) II 194 (47.4) 89 (46.6) III 126 (30.8) 62 (32.5) IV 26 (6.4) 14 (7.3) V 1 (0.2) 1 (0.5) VI 0 0 Other skin conditions, n (%) Eczema 69 (16.9) 31 (16.2) Psoriasis 38 (9.3) 16 (8.4) Facial cystic acne 12 (2.9) 14 (7.3) Hyperpigmentation 6 (1.5) 5 (2.6) Melasma 8 (2.0) 2 (1.0) None 300 (73.3) 135 (70.7) Age at Brst rosacea Signs/symptoms n 259 132 Mean (SD) 39.1 (15.40) 35.7 (14.45) Median (min, max) 40 (10, 72) 35 (10, 73) Cannot recall, n (%) 143 (35.0) 57 (29.8) ETR=erythematotelangiectatic rosacea; max= maximum; min=minimum; PPR=papulopustular rosacea; SD=standard deviation O R I G I N A L R E S E A R C h

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