Journal of Clinical and Aesthetic Dermatology

APR 2017

An evidence-based, peer-reviewed journal for practicing clinicians in the field of dermatology

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Page 13 of 64

E xcerpted Title Goes Here (continued) 14 Epub 2016 Mar 1. Synopsis: Here, authors review possible ocular side effects of using benzocaine, lidocaine, and tetracaine as topical anesthetics in the field of dermatology. PMID: 27354889; PMCID: PMC4896822 Topical local anesthesia: focus on lidocaine-tetracaine combination. Giordano D, Raso MG, Pernice C, et al. Local Reg Anesth. 2015;8:95–100. eCollection 2015 Nov 27. Synopsis: Authors describe the recent literature on safety and effectiveness of using the lidocaine/tetracaine combination therapy as a topical anesthetic in cosmetic procedures. PMID: 26664201; PMCID: PMC4669927 Body contouring and skin tightening A systematic review of paradoxical adipose hyperplasia (PAH) post- cryolipolysis. Ho D, Jagdeo J. J Drugs Dermatol. 2017;16(1):62–67. Synopsis: Authors reviewed the literature on paradoxical adipose hyperplasia postcryolipolysis ("fat- freezing"). Based on 10 records and 16 cases, they found that cryolipolysis was an effective noninvasive option for body contouring, but incidence of paradoxical adipose hyperplasia was higher than expected, possibly because some adipocytes may be selected for survival due to pre-existing resistance to the process. PMID: 28095535 Safety and efficacy of a non-contact radiofrequency device for body contouring in Asians. Suh DH, Kim CM, Lee SJ, et al. J Cosmet Laser Ther. 2017;19(2):89–92. Epub 2017 Feb 1. Synopsis: To assess clinical, radiological results of the radiofrequency, noncontact, selective- field device treatment for noninvasive reduction of subcutaneous abdominal fat, investigators treated 12 healthy volunteers with five 45-minute sessions at one-week intervals. They found that 10 of the volunteers showed reduction in abdominal circumference and conclude that selective-field radiofrequency is a safe and effective treatment for reduction of abdominal subcutaneous fat. PMID: 27834494 Use of a novel combined radiofrequency and ultrasound device for lipolysis, skin tightening and to treat cellulite. Kapoor R, Shome D, Ranjan A. J Cosmet Laser Ther. 2017 Mar 10. [Epub ahead of print] Synopsis: Researchers assessed changes in abdominal circumference and/or thigh circumference and appearance of cellulite in 275 patients (235 female) who received three treatment sessions of an alternating hot and cold ultrasound and radiofrequency technology for lipolysis. Authors found that most patients showed improvement in abdominal and/or thigh circumferences and conclude that the treatment was safe and effective. PMID: 28281840 Improved neocollagenesis and skin mechanical properties after injection of diluted calcium hydroxylapatite in the neck and dé colletage: a pilot study. Yutskovskaya YA, Kogan EA. J Drugs Dermatol. 2017;16(1):68–74. Synopsis: Researchers evaluated the ability of diluted calcium hydroxylapatite to stimulate collagen and elastin in individuals with skin laxity in the neck and dé colletage, by administering multiple, linear, subdermal injections to 20 individuals at three dilutions: 1:2 (normal skin), 1:4 (thin skin), and 1:6 (atrophic skin). Authors found significant increases in collagen I and III expression compared to baseline, improvements in skin elasticity and pliability, and increases in dermal thickness, and conclude that this treatment is effective for skin tightening of the neck and dé colletage. PMID: 28095536 Triple hedgehog pathway inhibition in the treatment of basal cell carcinoma Metastatic spinal cord compression from basal cell carcinoma of the skin treated with surgical decompression and vismodegib: case report and review of Hedgehog signalling pathway inhibition in advanced basal cell carcinoma. McGrane J, et al. Clin Exp Dermatol. 2017;42(1):80–83. Synopsis: In this case study, authors describe diagnosis and treatment of locally advanced and metastatic basal cell carcinoma causing spinal cord compression. The chest wall lesion that could not fully be covered by JCAD journal of clinical and aesthetic dermatology April 2017 • Volume 10 • Number 4 JOURNAL WATCH (continued)

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